论文部分内容阅读
目的研究A型肉毒毒素注射联合功能训练对痉挛型脑瘫患儿运动能力的影响。方法选取2014年1月-2015年1月该院收治的痉挛型脑瘫患儿120例为研究对象,按照随机数字表法将患者分为研究组和对照组,每组60例,对照组给予功能训练,研究组在对照组的基础上给予A型肉毒毒素注射治疗,比较治疗前后2周、1个月、3个月以及6个月应用综合痉挛量表(CSS)评分和粗大运动功能量表(GMFM)评分。结果研究组治疗2周后CSS评分开始降低,对照组治疗1个月后CSS评分开始降低,研究组治疗后与治疗前比较差异均有统计学意义(均P<0.05);两组治疗2周、1个月、3个月及6个月CSS评分比较,差异有统计学意义(P<0.05)。研究组治疗1个月后GMFM评分显著升高,对照组治疗6个月后GMFM评分显著提高,研究组治疗后与治疗前比较差异均有统计学意义(均P<0.05),两组治疗1个月、3个月及6个月GMFM评分比较差异均有统计学意义(均P<0.05)。结论 A型肉毒毒素注射联合功能训练治疗痉挛型脑瘫患儿能有效缓解肢体痉挛,提高患儿粗大运动能力。
Objective To study the effects of botulinum toxin type A injection combined with functional training on motor function in children with spastic cerebral palsy. Methods From January 2014 to January 2015, 120 children with spastic cerebral palsy who were treated in this hospital were selected as the research objects. According to the random number table, the patients were divided into study group and control group, 60 cases in each group. The control group was given function Training group was given botulinum toxin type A injection on the basis of the control group. The CSS scores and gross motor function were compared at 2 weeks, 1 month, 3 months and 6 months before and after treatment. Table (GMFM) score. Results After 2 weeks of treatment, the CSS score began to decrease in the study group, and the CSS score began to decrease after 1 month in the control group. The difference between the study group and before treatment was statistically significant (both P <0.05) , 1 month, 3 months and 6 months CSS score, the difference was statistically significant (P <0.05). After 1 month of treatment, the GMFM score of the study group was significantly increased, while the GMFM score of the control group increased significantly after 6 months of treatment. The difference between the study group and the pre-treatment group was statistically significant (both P <0.05) The differences of GMFM scores between months, 3 months and 6 months were statistically significant (all P <0.05). Conclusion Botulinum toxin A combined with functional training can effectively relieve limb spasm and improve children’s gross motor ability in children with spastic cerebral palsy.