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目的了解广东省珠海市2008-2011年围产儿唇腭裂的流行病学特征。方法利用珠海市出生缺陷监测系统获得围产儿唇腭裂资料并进行统计分析。结果珠海市2008-2011年围产儿总唇腭裂222例,发病率为21.77/万,各年度发病率差异无统计学意义;不同性别、产妇各年龄组发病率差异无统计学意义,城镇组发病率高于农村组;40.50%唇腭裂患儿在围生期死亡。结论珠海市围产儿唇腭裂发病率水平相对稳定,发病率较高,应采取综合措施加强围产儿唇腭裂的三级预防。
Objective To understand the epidemiological characteristics of perinatal children with cleft lip and palate from 2008 to 2011 in Zhuhai, Guangdong Province. Methods Zhuhai Birth Defects Monitoring System was used to obtain the data of perinatal cleft lip and palate and statistical analysis. Results There were 222 cases of perinatal total cleft lip and palate in Zhuhai from 2008 to 2011, with an incidence rate of 21.77 / million. There was no significant difference in the incidence of each year among different sexes and maternal age groups. There was no significant difference in morbidity between urban and males Rate was higher than that of rural group; 40.50% of children with cleft lip and palate died during the perinatal period. Conclusion The prevalence of cleft lip and palate in perinatal children is relatively stable and the incidence is high in Zhuhai. Comprehensive measures should be taken to strengthen the tertiary prevention of cleft lip and palate.