本文报告2例脑膜炎球菌性脑膜炎并发肺水肿病例,其中1例肺动脉楔压增高。例1:21岁,男性,血涂片找到固紫染色阴性球菌,诊断为脑膜炎球菌性败血症型。入院后给予氢化可的松、磺胺二甲基嘧啶和青霉素治疗,但病情迅速恶化,患者极度烦躁不安,并出现严重的呼吸困难,咳出大量泡沫样痰,抢救无效死亡。尸检证实为基底性脑膜炎,并有临终期肺炎,右心室显著扩张,肾上腺部分出血水肿。例2:19岁,男性,发病3小时入院。脑脊液检查:蛋白650毫克％,糖31毫克％,镜检:中性多核细胞10,500/立方毫米,红细胞5,500/立方毫米,脑脊液培养有少量脑膜炎球菌属菌生长。即用磺胺二甲基嘧啶注射和青霉素鞘内注射治疗。入院6小时后出现肺 This article reports 2 cases of meningococcal meningitis complicated by pulmonary edema cases, including 1 case of pulmonary artery wedge pressure increased. Example 1:21 years old, male, blood smears found solid purple stain negative cocci, diagnosis of meningococcal septicemia. After admission to give hydrocortisone, sulfamethazine and penicillin treatment, but the condition deteriorated rapidly, the patient was extremely irritable, and severe dyspnea, coughing a lot of foam-like sputum, rescue died of ineffectiveness. Autopsy confirmed basal meningitis, and a terminal pneumonia, a significant expansion of the right ventricle, adrenal hemorrhage and edema. Example 2: 19 years old, male, 3 hours after onset of admission. Cerebrospinal fluid examination: protein 650 mg%, sugar 31 mg%, microscopy: neutral multinucleated cells 10,500 / cubic millimeter, red blood cells 5,500 / cubic millimeter, cerebrospinal fluid culture with a small amount of meningococcal growth. Namely sulfamethoxazole injection and penicillin intrathecal injection therapy. Six hours after admission, the lungs appeared