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目的 评价丽珠胃三联(Livzon WeiSanlian)联合兰索拉唑(lansoprazole)根除幽门螺杆菌(Helicobacter pylori.Hp)和治疗相关性消化性溃疡(peptic ulcer,PU)的效果。资料与方法:将61例Hp相关性PU病人随机分为丽珠胃三联+兰索拉唑组(A组)和兰索拉唑组(B组)。A组:枸橼酸镁铋钾110mg,4/d,替硝唑0.5.2/d,克拉霉素025,3/d,兰索拉唑30mg,1/d,连续1周,B组 兰索拉唑30mg,1/d,阿莫西林0 5,3/d,甲硝唑200mg 3/d,连续2周,疗程结束后继续服用兰索拉唑到4周。停药4周后复查电子胃镜及~(14)C呼吸试验。结果:A组Hp根除率(96.7％)明显高于B组(83.9％)(P<0.05),A组的溃疡愈合率(900％)、总有效率(967％)高于B组(83.9％、903％),A组的疼痛消失时间、症状消失率亦较B组快,但均无显著差异(P>0 05),两组均无明显副作用。结论:丽珠胃三联联合兰索拉唑能有效根除Hp,对PU有较高的治愈率和症状缓解率,且副作用小。
Objective To evaluate the efficacy of Livzon WeiSanlian combined with lansoprazole in the treatment of Helicobacter pylori (Hp) and the treatment of peptic ulcer (PU). Materials and Methods: Sixty-one Hp-related PU patients were randomly divided into Livzon stomach triple combined with Lansoprazole group (A group) and lansoprazole group (B group). Group A: Magnesium bismuth potassium citrate 110mg, 4 / d, tinidazole 0.5.2 / d, clarithromycin 025,3 / d, lansoprazole 30mg, 1 / d, Sorazole 30mg, 1 / d, amoxicillin 0 5,3 / d, metronidazole 200mg 3 / d, for 2 weeks, after the end of the course of lansoprazole to continue to 4 weeks. After 4 weeks of discontinuation of electronic gastroscopy and ~ (14) C breathing test. Results: The Hp eradication rate in group A was significantly higher than that in group B (96.7% vs 83.9%, P <0.05). The healing rate of group A was 900% and the total effective rate was 967% %, 903%). The pain disappear time and symptom disappearance rate in group A were also faster than those in group B, but there was no significant difference (P> 0.05). There was no obvious side effect in both groups. Conclusion: Livzon stomach combined with Lansoprazole can effectively eradicate Hp, and has higher cure rate and symptom relief rate to PU, with less side effects.