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目的研究脑梗死后出血性转化与脑内微出血(CMB)的相关性。方法 200例急性脑梗死患者,进行各种相关危险因素、一般资料的记录,确定CMB的部位、数目,随后对急性脑梗死患者按照缺血性卒中指南进行处理及治疗,对出现出血性转化(HT)的患者及无出现脑梗死后HT的患者均进行CMB的统计,明确脑内微出血和脑梗死后出血性转化相关性。结果在有出血转化组(HT组)中有24例(35.3%)通过磁共振检查到有脑内微出血出现,无出血转化组(无HT组)仅有16例(12.1%),两组出现率比较差异有统计学意义(P<0.05)。HT组患者IMBs出现平均数目较无HT组高,HT组患者转化HT组并发症比率高,死亡率高,预后差(P<0.05)。结论脑梗死后出血转组患者脑内微出血检出率较无出血转化组高,脑梗死后出血转化与脑内微出血呈正相关,考虑脑内微出血可以作为脑梗死患者出现出血转化情况的预测因素之一。
Objective To study the correlation between hemorrhagic transformation after cerebral infarction and intracerebral hemorrhage (CMB). Methods A total of 200 patients with acute cerebral infarction were enrolled in this study. All the relevant risk factors and general data were recorded. The number and location of CMB were determined. The patients with acute cerebral infarction were treated and treated according to the ischemic stroke guidelines. HT) and patients without HT after cerebral infarction were performed CMB statistics, a clear understanding of intracerebral hemorrhage and cerebral hemorrhagic transformation associated. Results In the hemorrhagic transformation group (HT group), 24 cases (35.3%) had intracerebral hemorrhage by magnetic resonance imaging. There were only 16 cases (12.1%) without hemorrhage conversion group (HT group) There was significant difference in the incidence (P <0.05). The average number of IMBs in HT group was higher than that in HT group. The HT group had higher complication rate, higher mortality and poor prognosis (P <0.05). Conclusion The detection rate of intracerebral hemorrhage in patients with hemorrhage and transfusion after cerebral infarction is higher than that in hemorrhage and non-hemorrhage transfusion group. The hemorrhage conversion after cerebral infarction is positively correlated with intracerebral hemorrhage. Considering intracerebral hemorrhage can be used as a hemorrhagic transformation in patients with cerebral infarction One of the predictors.