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卵巢功能正常的妇女股骨密度在20岁时达到高峰。性激素在维持骨密度方面起重要作用,卵巢功能停止将导致明显的骨丢失。从1988年12月～1993年1月,对要求生育的89例染色体正常的特发性卵巢早衰妇女,采用常规双光子吸收比色法进行髋(股骨颈、Ward’s三角和股骨转子)和脊柱(L2～4)骨质密度测定。纳入条件:40岁以下,闭经4个月以上,FSH2次>40IU/L(间隔1个月以上)。医源性或染色体异常的卵巢衰竭病人除外。检测项目:病史,体格检查,染色体核型检查,髋和脊柱骨密度测定,以及与卵巢早衰有关的自身免疫所致内分泌紊乱的检查。均用同一设备完成,以使检测结果具有可比性。
Females with normal ovarian function peaked at 20 years of age. Sex hormones play an important role in maintaining bone density, and stopping ovarian function leads to significant bone loss. From December 1988 to January 1993, 89 preterm women with idiopathic idiopathic premature ovarian failure who required fertility were treated with conventional two-photon absorption colorimetry for hip (femoral neck, Ward’s triangle and femoral trochanter) and spine L2 ~ 4) Determination of bone density. Inclusion conditions: 40 years of age, amenorrhea for more than 4 months, FSH2 times> 40IU / L (interval of more than 1 month). Iatrogenic or chromosomal abnormalities other than ovarian failure patients. Test items: medical history, physical examination, karyotype examination, measurement of hip and spine bone mineral density, and examination of endocrine disorders caused by autoimmune associated with premature ovarian failure. The same equipment are used to make the test results comparable.