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目的观察纳洛酮治疗院前发生急性呼吸衰竭患者的效果。方法 46例院前发生急性呼吸衰竭患者,随机分为观察组与对照组,各23例。观察组给予纳洛酮治疗,对照组给予可刹米治疗,对两组患者临床治疗效果进行比较。结果观察组总有效率为86.96%,对照组总有效率为60.87%,观察组总有效率高于对照组,差异有统计学意义(P<0.05);用药1 h后,观察组血氧分压(Pa O2)、血二氧化碳分压(Pa CO2)、血氧饱和度(Sp O2)均优于对照组,差异均有统计学意义(P<0.05)。结论给予院前发生急性呼吸衰竭患者纳洛酮治疗的效果显著,值得在临床上推广。
Objective To observe the effect of naloxone in the treatment of acute respiratory failure in hospital. Methods 46 patients with acute respiratory failure before hospital were randomly divided into observation group and control group, 23 cases in each. The observation group was treated with naloxone, while the control group was given cetamazide. The clinical effects of the two groups were compared. Results The total effective rate was 86.96% in the observation group and 60.87% in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05) PaO2, PaCO2 and SpO2 were all better than those in the control group (P <0.05). Conclusion The effect of naloxone treatment in patients with acute respiratory failure before hospital is significant and worthy of clinical promotion.