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目的 研究糙叶败酱中一个新的环烯醚萜苷元成分体外抗肿瘤作用。方法 采用四唑盐 (MTT)比色法研究糙叶败酱中环烯醚萜苷元成分对人前列腺癌细胞株DU1 4 5和PC3生长的影响。结果 PS I可显著抑制人前列腺癌细胞株DU1 4 5和PC3生长 ,并且具有一定的时间、剂量依赖关系。结论 环烯醚萜苷元PS I是糙叶败酱抗肿瘤作用的活性成分之一。
Aim To study the anti-tumor effect of a new iridoid aglycone in Paeonia suffruticosa. Methods MTT assay was used to study the effects of iridoid glycosides on the growth of human prostate cancer cell lines DU1 45 and PC3. Results PS I significantly inhibited the growth of human prostate cancer cell lines DU1 45 and PC3, and had a certain time-and dose-dependent relationship. Conclusion Iridoid aglycone PS I is one of the active ingredients against the antitumor effect of Carambola.