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目的:观察急性心肌梗死(AMI)静脉溶栓治疗的疗效。方法:选用我院2007年收治的AMI患者40例,其中男30例,女10例,年龄29～74岁,平均56.2岁,全部病例均符合WHO规定的AMI诊断标准,治疗均给予尿激酶150万U,加0.9%氯化钠溶液100ml,静脉点滴,30min滴完。结果:本组无一例死亡,梗死相关的冠状动脉总再通率为65.0%,3h内溶栓再通率为78.3%(18/23),3～6h溶栓再通率为4⒎1%(8/17),两者相比差异有统计学意义(P<0.05)。再灌注心律失常率为73.1%。有2例出现静脉穿刺部位皮肤淤血,1例出现寒战、高热,无消化道及脑出血。结论:静脉溶栓疗法降低AMI病死率,改善预后,显著改变AMI自然病程,疗效快效果好,适宜在基层医院推广。
Objective: To observe the curative effect of intravenous thrombolysis in acute myocardial infarction (AMI). Methods: Forty patients with AMI who were admitted to our hospital in 2007 were selected, including 30 males and 10 females, aged 29-74 years (average 56.2 years). All cases were in accordance with the WHO diagnostic criteria for AMI. All patients were given urokinase 150 Wan U, add 0.9% sodium chloride solution 100ml, intravenous drip, 30min drip finished. Results: There was no death in this group, the total recanalization rate of infarction-related coronary artery was 65.0%, the recanalization rate of thrombolysis within 3 hours was 78.3% (18/23), the recanalization rate of thrombolysis from 3 to 6 hours was 4% to 1% / 17), the difference was statistically significant (P <0.05). The rate of reperfusion arrhythmia was 73.1%. There were 2 cases of venous venous congestion in the skin, 1 case of chills, fever, no gastrointestinal and cerebral hemorrhage. Conclusion: Intravenous thrombolytic therapy can reduce AMI mortality, improve prognosis and significantly change the natural course of AMI. The curative effect is quick and effective and is suitable for promotion in primary hospitals.