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我们自1993年起即以FT_3、FT_4、HS-TSH替代了过去应用TT_3、TT_4、TSH、FTIU。应用至今实感有很大的应用价值,现就我们应用的结果报道如下。 材料和方法 一、对象: (一)正常对照组:192例(男54、女138),年龄19~61岁。均为无异常甲功的健康体检人员血清。 (二)甲状腺机能亢进病人:792例(男184,女608),年龄9~76岁。来源于门诊及住院病人。 二、方法: FT_3、FT_4试剂盒由上海原子能所提供;HS-TSH由中国医学科学院核医学技术中心提供,均按说明书操作。 结果 三种激素测定结果如表1所见,甲亢组与对照组比较FT_3、FT_4、HS-TSH差别非常显著(p<0.001)。依次比对照组>4、>3.6、>11倍。疑诊甲低组与对照组比较也具有同样的显著性差别(p<0.001);依次比对照组<3、<3.3、<30倍。可见,无论甲亢或甲低首选指标是HS-TSH。对甲亢诊断依
We have replaced TT_3, TT_4, TSH and FTIU with FT_3, FT_4 and HS-TSH since 1993. The application so far has a great practical value, now the results of our application reported below. Materials and methods First, the object: (a) normal control group: 192 cases (54 men and 138 women), aged 19 to 61 years old. No abnormality of a successful physical examination of the serum. (B) hyperthyroidism patients: 792 cases (male 184, female 608), aged 9 to 76 years. From outpatient and inpatient. Second, the method: FT_3, FT_4 kit provided by the Shanghai Atomic Energy; HS-TSH by the Chinese Academy of Medical Sciences Nuclear Medicine Technology Center, according to the instructions. Results The results of three hormones as shown in Table 1, hyperthyroidism group compared with the control group FT_3, FT_4, HS-TSH difference was significant (p <0.001). Followed by the control group> 4,> 3.6,> 11 times. Suspected hypothyroidism with the control group also had the same significant difference (p <0.001); followed by the control group <3, <3.3, <30 times. Can be seen, regardless of hyperthyroidism or hypothyroidism preferred indicator is HS-TSH. According to the diagnosis of hyperthyroidism