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目的探讨米索前列醇在无痛人工流产术时用于软化宫颈的临床效果。方法将200例无痛人工流产的妇女随机分为观察组和对照组,每组100例,观察组术前2h阴道置米索前列醇400μg,对照组不给予米索前列醇。结果宫颈松弛效果比较,观察组总有效率为93%,明显好于对照组的35%(P<0.01);观察组手术时间(2.92±1.06)min,短于对照组的(4.96±1.56)min,差异有统计学意义(P<0.05);观察组术中出血量(9.76±3.68)ml,少于对照组的(20.12±5.12)ml。结论米索前列醇配合早孕无痛人工流产,有效地松弛了宫颈,大大降低了手术风险,方法简便易行,可在临床上推广应用。
Objective To investigate the clinical effect of misoprostol in softening cervix during painless artificial abortion. Methods 200 cases of painless abortion women were randomly divided into observation group and control group, with 100 cases in each group. The observation group received vaginal misoprostol 400μg 2 hours before operation and the control group did not receive misoprostol. Results The total effective rate in the observation group was 93%, which was significantly better than that in the control group (P <0.01). The operative time in the observation group (2.92 ± 1.06) min was shorter than that in the control group (4.96 ± 1.56) min, the difference was statistically significant (P <0.05). The bleeding volume in the observation group was (9.76 ± 3.68) ml less than that of the control group (20.12 ± 5.12) ml. Conclusion Misoprostol combined with painless induced abortion in early pregnancy effectively relaxes the cervix and greatly reduces the operation risk. The method is simple and easy to be applied in clinical practice.