论文部分内容阅读
目的探讨结直肠癌合并恶性胸腹腔积液的预后因素。方法回顾性分析2001年1月至2010年12月中国医学科学院肿瘤医院内科结直肠癌合并恶性胸腹腔积液患者的临床资料。结果 44例患者中,治疗后积液完全消失2例,减少16例,稳定6例,增多20例。中位总生存时间为8个月。单因素分析结果显示,KPS评分、肝转移、治疗模式、积液控制率、白蛋白以及胆红素水平与总生存时间有关。结论 KPS评分≥80分、无肝转移、全身化疗、积液控制好、白蛋白和胆红素水平正常的患者预后更好。
Objective To investigate the prognostic factors of colorectal cancer complicated with malignant pleural effusion. Methods The clinical data of patients with colorectal cancer complicated with malignant pleural effusion and ascites from January 2001 to December 2010 in Cancer Hospital of Chinese Academy of Medical Sciences were retrospectively analyzed. Results Among the 44 patients, effusion completely disappeared in 2 cases, decreased in 16 cases, stabilized in 6 cases and increased in 20 cases. The median overall survival was 8 months. Univariate analysis showed that KPS score, liver metastases, treatment modalities, fluid control rate, albumin and bilirubin levels were associated with overall survival. Conclusion KPS score ≥ 80 points, no liver metastasis, systemic chemotherapy, fluid control, patients with normal albumin and bilirubin levels have a better prognosis.