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目的 33例乳腺癌发生骨转移临床分析。方法 回顾分析了33例乳腺癌发生骨转移的年龄、病理分型、术前临床分期、转移部位、术后辅助性化疗情况及骨转移部位。结果 本组33例乳腺癌发生骨转移的中位年龄为45岁,病理均为乳腺浸润性非特殊型癌,ER阳性13例,阴性20例。术前临床分期:Ⅲ期15例(45.5％),术后辅助性化疗不规范。发生骨转移的部位以椎骨最多11例(33.3％),其次为盆骨8例(24.2％)。结论 对年龄轻、病理分型差、临床分期较晚的乳腺癌病人应进行正规治疗降低骨转移发生率。
Objective To analyze the bone metastasis of 33 cases of breast cancer. Methods The age, pathological type, preoperative clinical stage, site of metastasis, postoperative adjuvant chemotherapy and bone metastasis in 33 patients with bone metastases were retrospectively analyzed. Results The median age of bone metastases in 33 cases of breast cancer in this group was 45 years old. Pathologically, there were breast infiltrating nonspecific cancers, ER positive in 13 cases and negative in 20 cases. Preoperative clinical stage: 15 cases (45.5%) in stage III, postoperative adjuvant chemotherapy was not standardized. The site of bone metastasis was up to 11 cases (33.3%) of vertebrae, followed by 8 cases (24.2%) of pelvis. Conclusion For the breast cancer patients with younger age, poor pathological classification and later clinical stage, regular treatment should be performed to reduce the incidence of bone metastases.