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目的:对反映帕金森病患者运动功能障碍的评分量表——帕金森病运动功能评分量(motordysfunctionratingscaleforParkinson’sdiseaese,MDR-SPD)的一致性和敏感性的评定,体现其优越性。方法:对5个评定者之间用MDRSPD评价20例帕金森病患者的运动功能的评分结果做Kappa检验;对另20例帕金森病患者治疗前后的评分结果进行t检验。结果:该量表15个项目的Kappa检验,最低K=0.66,最高K=0.97;20例帕金森病患者治疗前后得分分别为(19.68±7.94),(16.03±7.19)分,治疗前后评分结果差异有显著性意义(t=7.13,P<0.001)。结论:MDRSPD评定者之间一致性良好,且能敏感地反映出病情变化,可用于帕金森病患者的病情严重程度和治疗疗效的评定。
OBJECTIVE: To evaluate the consistency and sensitivity of motility function scale (Parkinson’s disease motor score) reflecting the motor dysfunction in patients with Parkinson’s disease and to show its superiority. Methods: The Kappa test was used to evaluate the motor function of 20 patients with Parkinson’s disease evaluated by MDRSPD among 5 assessors. The scores of other 20 patients with Parkinson’s disease before and after treatment were analyzed by t-test. Results: The Kappa test of 15 items in this scale showed the lowest K = 0.66 and the highest K = 0.97. Before and after treatment, the scores of 20 patients with Parkinson’s disease were (19.68 ± 7.94) and (16.03 ± 7.19), respectively The difference was significant (t = 7.13, P <0.001). Conclusion: The consistency between MDRSPD assessors is good, and it can reflect the change of disease sensitively, which can be used to evaluate the severity of disease and curative effect of Parkinson ’s disease patients.