论文部分内容阅读
目的探讨小儿格林-巴利综合征（GBS）病因、发病机制、防治措施。方法对青州市242例GBS患儿进行回顾性流行病学调查、临床观察、免疫学检测及微量元素检测。结果242例GBS患儿52．81％发病年龄为3～6a，75．61％发病时间在7～9月份，98．7％来自农村，年发病数3～40例，52．17％血清抗神经抗体阳性，平均血清锌含量9．12±0．56μmol／L。补锌治疗可促进康复。结论青州市小儿GBS发病年龄、季节、区域、年发病数有明显差异，患儿存在免疫紊乱及微量元素锌缺乏。
Objective To investigate the etiology, pathogenesis and prevention and treatment of children with Guillain-Barre syndrome (GBS). Methods A retrospective epidemiological investigation, clinical observation, immunological test and trace element test were performed on 242 children with GBS in Qingzhou. Results 52.81% of 242 children with GBS had an age of 3 ~ 6a. The onset time was 75.61% in July ~ September and 98.7% of them were from rural areas. The annual incidence was 3 ~ 40 cases and 52.17% Positive antibody, the average serum zinc content 9.12 ± 0.56μmol / L. Zinc treatment can promote rehabilitation. Conclusion The age, season, area and annual incidence of pediatric GBS in Qingzhou are obviously different. There is immune disorder and zinc deficiency in children.