环胞多肽(Cyclosporin,CyS)是一种免疫抑制剂,其作用是激活T辅助淋巴细胞。根据Baker等人银屑痫(Ps)的发病与T辅助淋巴细胞有关的设想,以及在随后的研究中证实,使用CyS治疗Ps是有效的。既往都是短期使用CyS治疗Ps,停药后病情易复发。由于Ps是一种慢性疾病,同时CyS又没有快速免疫抑制作用。所以,要以小剂量、长期维持的原则。使皮损逐步得到改善。 Cyclosporin (CyS) is an immunosuppressive agent that acts to activate T helper lymphocytes. According to the hypothesis of Baker et al. On the pathogenesis of psoriatic eclampsia (Ps) associated with T-helper lymphocytes, and in subsequent studies it has been demonstrated that treatment of Ps with CyS is effective. Past use of CyS are short-term treatment of Ps, after stopping the disease is easy to relapse. Because Ps is a chronic disease, CyS has no rapid immunosuppression. So, to a small dose, the principle of long-term maintenance. The skin lesions gradually improved.