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目的：观察曲马朵对分娩的镇痛效果及对产程、母婴的影响。方法：单胎初产妇共１４６例（年龄２５．０±ｓ１．０ａ；孕周３９．０±１．６ｗｋ）。在产妇子宫口开大２～４ｃｍ时，５２例用曲马朵胶囊１００ｍｇｐｏ，日用量３００ｍｇ以内；４７例用地西泮１０ｍｇ，ｉｖ；不用药组４７例。结果：曲马朵组镇痛效果肯定，与另２组比较Ｐ＜０．０１。分娩第一产程时间与地西泮组无差别，Ｐ＞０．０５，而明显优于不用药组（Ｐ＜０．０１）。３组产妇产后出血量、分娩方式、产后１～１０ｍｉｎ新生儿Ａｐｇａｒ评分及脐血血气分析无差异。结论：曲马朵用于分娩镇痛效果满意
Objective: To observe the effect of tramadol on childbirth analgesia and labor process, maternal and infant. Methods: A single mothers a total of 146 cases (age 25.0 ± s1.0a; gestational age 39.0 ± 1.6wk). In the maternal uterine opening large 2 ~ 4cm, 52 cases of tramadol capsules 100mgpo, 300mg daily dosage; 47 cases with diazepam 10mg, iv; no medication group 47 cases. Results: Tramadol group analgesic effect was positive, compared with the other two groups P <0.01. There was no difference between the first delivery stage and the diazepam group (P> 0.05), but it was significantly better than that of the non-medication group (P <0.01). 3 groups of postpartum hemorrhage, mode of delivery, neonatal Apgar score 1 ~ 10 postpartum and umbilical cord blood gas analysis no difference. Conclusion: Tramadol for labor analgesia with satisfactory results