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去纤酶(defibrinogenase)系从我国湖南省产尖吻腹蛇蛇毒中提取。临床用以治疗闭塞性血管病取得满意疗效。作者报告以小剂量(1NIH精氨酸酯酶单位)去纤酶加入生理盐水500ml中静滴治疗冠心病35例,隔3天一次,连用3次。心绞痛有效率79%,显效率51%;心电图心肌缺血有效率72%,显效率32%。与综合疗法治疗的对照组比较无明显差异。作者通过有限病例观察,认为去纤酶疗效较高,副作用少,不失为治疗冠心病的有效药物之一。
Defibrinogenase was extracted from the snakehead snake venom in Hunan province of China. Clinically used to treat occlusive vascular disease achieved satisfactory results. The authors report a small dose (1NIH arginine esterase units) defibrase added 500ml of normal saline in the treatment of coronary heart disease 35 cases, once every 3 days, once every 3 times. Angina pectoris effective rate of 79%, markedly effective rate of 51%; electrocardiogram myocardial ischemic effective rate of 72%, markedly effective rate of 32%. There was no significant difference between the treatment group and the control group. Through a limited number of cases the author believes that defibrase high efficacy, fewer side effects, after all, one of the effective drugs for the treatment of coronary heart disease.