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本文分析了8例原发性慢性进展型多发性硬化(PCPMS),具有发病年龄较晚,男性比例较高;视神经炎较少,中枢损害较多;脑脊液炎性改变较少,CT、MRI及诱发电位的阳性率较高;皮质类固醇疗效较差以及近期预后较好、远期预后较差等临床特征。指出PCPMS是多发性硬化的一个特殊的、独立的临床类型。
In this paper, 8 cases of primary chronic progressive multiple sclerosis (PCPMS) were analyzed, with a younger age, a higher proportion of males, fewer optic neuritis and more central lesions, less inflammatory changes in cerebrospinal fluid, CT, MRI and The positive rate of evoked potentials higher; poor efficacy of corticosteroids and the recent prognosis is good, poor prognosis and other clinical features. Pointed out that PCPMS is a special, independent clinical type of multiple sclerosis.