成神經細胞瘤成神经细胞瘤早期诊断比较困难,症状常不典型。早期症状常表现为风湿样的疼痛或胃肠炎,很多被误诊为风湿热或婴儿泄泻,Koop认为前者常因肿瘤转移到骨与关节,因而发生疼痛和发热,后者与肿瘤本身分泌去甲肾上腺素有关。因此,对于上述症状在诊断时必须注意鉴別。最近发现成神经细胞瘤病儿,有一种特殊的临床类型,表现为高血压症状。1957年Mason首先在一例纵隔成神经细胞瘤发现有阵发性 Neuroblastoma neuroblastoma early diagnosis is more difficult, the symptoms are often atypical. Early symptoms often appear rheumatic pain or gastroenteritis, many were misdiagnosed as rheumatic fever or infant diarrhea, Koop that the former often due to tumor metastasis to bone and joint, which occurred pain and fever, the latter secreted with the tumor itself Norepinephrine related. Therefore, in the diagnosis of the above symptoms must pay attention to identification. Recently found that neuroblastoma children, there is a special type of clinical manifestations of hypertension. In 1957 Mason first found in one case of mediastinal neuroblastoma paroxysmal