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近年来大量研究已证实,哮喘是涉及多种细胞相互作用的一种慢性炎症性疾病。有关白细胞介素(IL)在炎症发生与持续中的作用已日益引起重视。下面就IL与哮喘的发病关系作一综述。1IL-1和IL-2IL-1是第一个被鉴定的。它主要由单核细胞、肥大细胞分泌。具有活性的IL-1可分为两种亚型:
In recent years, a large number of studies have confirmed that asthma is a chronic inflammatory disease involving a variety of cell interactions. The role of interleukin (IL) in the occurrence and persistence of inflammation has drawn increasing attention. The following IL and the pathogenesis of asthma are reviewed. 1 IL-1 and IL-2 IL-1 were the first to be identified. It is mainly secreted by monocytes, mast cells. The active IL-1 can be divided into two subtypes: