胃癌是世界性的健康问题。胃癌病人就诊往往较晚,以至诊断时疾病已处于晚期状态。胃癌病人的最重要的治疗方式是根治性手术切除,其重点是将并发症发生率和病死率降到最低。由于单纯手术治疗的局部、区域和全身的复发率较高,化疗和放疗已经成为这一肿瘤综合治疗的一部分。手术前和围手术期使用化、放疗最近已经获得多个临床试验的验证。虽然各地的标准治疗方案有所不同,但资料显示,多学科的综合治疗是胃癌病人改善结局的最好的模式。 Gastric cancer is a worldwide health problem. Patients with gastric cancer are often treated later, even when the disease is diagnosed in a late state. The most important treatment for patients with gastric cancer is a radical surgical resection, the focus of which is to minimize the incidence of complications and mortality. Chemotherapy and radiotherapy have become part of this comprehensive cancer treatment because of the high rate of local, regional and systemic recurrence of surgery alone. Preoperative and perioperative use of chemotherapy has recently been validated in several clinical trials. Although standard treatment regimens vary from place to place, data show that multidisciplinary general treatment is the best model for improving outcome in patients with gastric cancer.