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在西安市三所医院进行了孕妇生活事件与胎儿宫内生长迟缓(IUGR)的病例对照调查(1:1,155对),单因素分析表明 LUGR 组孕妇生活事件强度评分(51.36±11.24)明显高于对照组(43.17±12.36),生活事件以夫妻争执、重病外伤、家庭纠纷为主,分层分析表明孕生活事件与孕期热卡摄入量少具有相乘的联合作用。用多元条件 lo-gistic 分析控制其它因素后生活事件仍与 LUGR 有关(OR=2.27)。提出孕妇精神刺激可通过影响能量代谢或胎盘功能胎儿宫内生长延迟。
A case-control survey (1: 1,155 pairs) on pregnant women’s life events and intrauterine growth retardation (IUGR) was conducted at three hospitals in Xi’an. Univariate analysis showed that the intensity of life events of pregnant women in LUGR group (51.36 ± 11.24) was significantly higher than In the control group (43.17 ± 12.36), life events were mainly marital disputes, serious illness and trauma, and family disputes. Stratified analysis showed that synergistic effects of multiple pregnancies and pregnancy caloric intake were obtained. Life events were still related to LUGR after controlling for other factors using multivariate conditional lo-gistic analysis (OR = 2.27). Proposed mental stimulation of pregnant women can affect fetal energy metabolism or fetal growth retardation.