论文部分内容阅读
动物实验和临床观察均报告疟疾、血吸虫病和锥虫感染等3种主要热带寄生虫病都和肾脏病变有关联,并和肾小球毛细管壁上有免疫复合物沉积相一致。疟疾免疫复合物型肾脏损害有最令人信服的证据,并发现疟疾免疫复合物型肾脏主要病变有下述两类: (1)急性病变(短期可逆的):急性的实验动物模型,猴感染猴间日疟原虫后9天可在肾小球发现免疫球蛋白、补体及猴间日疟抗原沉积;小白鼠感染伯氏疟原虫后7天,发现在肾小球有伯氏疟原虫抗原的颗粒沉积,8
Animal experiments and clinical observations report that malaria, schistosomiasis and trypanosome infections are all associated with nephropathy and are consistent with immune complex deposition on the glomerular capillary wall. The most convincing evidence of kidney damage from malaria immune complexes is found and found that malaria immunocomplex-type renal major lesions are classified into the following two categories: (1) acute lesions (short-term reversible): acute experimental animal models of monkey infections 9 days after the Japanese Plasmodium vivax immunoglobulin can be found in the glomerulus, complement and monkey anti-Plasmodium antigen deposition; mice infected with bermudagrass 7 days after the found in the glomerular Plasmodium berghei antigen Particle deposition, 8