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[目的]探讨延长融合节段治疗腰椎滑脱并相邻节段椎间盘退变患者的中期疗效.[方法]2002年9月～2007年9月本科对79例腰椎滑脱并相邻节段退变的患者实施后路延长融合节段植骨内固定术,通过对患者术前及术后不同时期JOA评分、VAS评分进行比较,调查术后患者满意率,复查X线片及CT观察植骨融合及脊柱稳定性.[结果]术后随访2～6.5年,平均4.6年.术后不同时期JOA评分明显高于术前(P<0.05),VAS评分明显低于术前(P<0.05).依据JOA评分及VAS评分标准评定疗效:优61例,良10例,可7例,差1例,优良率达89.87%,未出现滑脱畸形加重、内固定松动断裂、伤口感染及神经损伤加重、腰椎间盘突出复发及顽同性腰痛等.[结论]延长融合节段治疗腰椎滑脱并相邻节段椎间盘退变,术后中期疗效满意.“,”[Objective]To investigate the metaphase result of extensive fusion in treatment of spondylolisthesis combined with intervertebral disc degeneration of adjacent joints. [Methods]Seventy-nine cases of lumbar spondylolisthesis combined with intervertebral disc degeneration of adjacent joints were treated with extensive fusion and internal fixation from September 2002 to September 2007. JOA and VAS scores were assessed and compared pre-and post-operatively. X-ray and CT were performed to observe the stabilization of fusion joints, and satisfaction rate from patients was investigated. [Results]All pa-tients were followed up for 2 to 6. 5 years (mean, 4. 6 years) . Post-operative JOA scores increased (P < 0. 05) and VAS scores decreased (P < 0. 05) significantly than pre-operative ones. According to JOA and VAS standard, there were 61 excel-lent results, 10 good, 7 fair, 1 poor, with good-to-excellent rate of 89. 87%. No complications was found such as aggravated formation, fixation broken, infection, aggravated neural injury, recurrence of herniation, back pain, et al. [Conclusion]Ex-tensive fusion has achieved good metaphase result in treatment of spondylolisthesis combined with intervertebral disc degeneration of adjacent joints.