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通过两亲单体2-丙烯酰胺基烷磺酸(AMCnS)与辛可宁(CN)成盐后再聚合,或AMCnS聚合成梳型两亲聚合物后再与CN成盐,可获得含辛可宁的两亲聚合物。AMCnS-CN盐及其相应的两亲聚合物(当n=6或16时)具有比CN好得多的溶解性,易溶于氯仿、THF、乙醇、DMF和DMSO等极性不同的溶剂。AMCnS-CN盐在乙醇/氯仿(V/V=1/2)中比旋光度等于辛可宁的比旋光度与辛可宁在盐中重量百分数的乘积,而相应两亲聚合物的比旋光度则不能用相似公式进行计算,说明聚合物主链对辛可宁单元的旋光性有重要影响。含CN的两亲聚合物与PAMC16S相似,在乙醇中显示聚电解质的典型特性
After amphoteric monomer 2-acrylamidoalkanesulfonic acid (AMCnS) is salified with cinchonine (CN), or AMCnS is polymerized into amphiphilic amphoteric polymer and salified with CN, two Pro-polymer. AMCnS-CN salts and their corresponding amphiphilic polymers (when n = 6 or 16) have much better solubility than CN and are readily soluble in solvents of different polarities such as chloroform, THF, ethanol, DMF and DMSO. The specific rotation of AMCnS-CN salt in ethanol / chloroform (V / V = 1/2) is equal to the product of the specific rotation of cinchonine and the weight fraction of cinchonine in salt, while the specific rotation of the corresponding amphiphilic polymer can not be used The calculation of the similar formula shows that the main chain of the polymer has an important influence on the optical activity of the cinchonine unit. Amphiphilic polymers containing CN are similar to PAMC16S and show the typical properties of polyelectrolytes in ethanol