论文部分内容阅读
一些报道表明,肿瘤坏死因子(TNFα)在许多急性细菌性脑膜炎患者的脑脊液(CSF)中的浓度升高,而无菌性脑膜炎儿童CSF中的TNFα浓度正常。为了确定检测CSF TNFα对鉴别细菌性和非细菌性脑膜炎的价值,作者进行了本研究。本研究中189例脑膜炎患者均有脑膜炎症状和CSF中淋巴细胞增多(≥5×10~6白细胞/L)。细菌性脑膜炎患者包括感染流感嗜血杆菌24例;肺炎链球菌14例;脑膜炎奈瑟氏菌7P例;其他细菌6例;结核分支杆菌6例;伯氏疏螺旋体4例。非细菌性脑膜炎患者包括感染肠病毒44例,单纯性疱疹病毒
Some reports indicate that tumor necrosis factor (TNFα) is elevated in the cerebrospinal fluid (CSF) of many patients with acute bacterial meningitis, while normal levels of TNFα are present in children with aseptic meningitis. In order to determine the value of detecting CSF TNFα for the differential diagnosis of bacterial and non-bacterial meningitis, the authors conducted this study. In our study, 189 patients with meningitis had meningitis symptoms and lymphocytosis (≥5 × 10 ~ 6 leukocytes / L) in CSF. Bacterial meningitis patients include Haemophilus influenzae infection in 24 cases; Streptococcus pneumoniae in 14 cases; Neisseria meningitidis 7P cases; 6 other bacteria; Mycobacterium tuberculosis in 6 cases; Borrelia burgdorferi in 4 cases. Patients with non-bacterial meningitis include 44 cases of enterovirus and herpes simplex virus