原发性肝细胞癌(HCC)的发病率居恶性肿瘤中第3位。由于该病无特异性临床表现,确诊时多为中晚期,且大于80%的病例同时伴有肝硬化,预后不良。根治性切除术是治疗HCC的主要手段,但术后高复发转移率已成为制约患者术后长期生存的瓶颈,有报道称根治性切除后5年复发率约为 The incidence of primary hepatocellular carcinoma (HCC) ranks third in malignant tumors. As the disease without specific clinical manifestations, mostly in the diagnosis of late, and more than 80% of cases accompanied by cirrhosis, poor prognosis. Radical resection is the main means of treatment of HCC, but postoperative high recurrence and metastasis rate has become a bottleneck restricting the long-term survival of patients after surgery, there are reports that 5 years after radical resection, the recurrence rate was about