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目的了解医院抗菌药物使用情况,为临床合理用药提供参考。方法调查2011年和2012年所有出院患者的临床资料,分析总体抗菌药物使用情况。结果 2011年和2012年的患者分别为41 691例和43 872例,与2011年相比,2012年医院患者在抗菌药物使用强度及抗菌药物使用率等指标上均有所下降,抗菌药物治疗的患者微生物检验样本送检率有所上升;两年抗菌药物临床使用均以氟喹诺酮类和青霉素类+酶抑制剂类为主,氟喹诺酮类的使用强度分别为10.88和11.29,青霉素类+酶抑制剂类的使用强度分别为9.22和8.13;左氧氟沙星、莫西沙星和头孢米诺的使用强度均排在前3位,2011年使用强度分别为5.29、4.56、4.74,2012年使用强度分别为5.66、5.10、3.85。结论医院抗菌药物管理在总体上已经取得一定效果,但在抗菌药物的使用上还需要出台具体措施,加强管理控制。
Objective To understand the use of antimicrobial drugs in hospitals and provide a reference for clinical rational drug use. Methods The clinical data of all discharged patients in 2011 and 2012 were investigated and the overall use of antibiotics was analyzed. Results The number of patients in 2011 and 2012 were 41 691 and 43 872, respectively. Compared with 2011, the number of hospital patients in 2012 decreased in terms of the strength of antimicrobial agents and the rate of antibacterial drug use. The antimicrobial treatment In the two years, the clinical use of antibacterials were mainly fluoroquinolones and penicillins + enzyme inhibitors, and the use intensities of fluoroquinolones were 10.88 and 11.29, respectively. Penicillins + enzyme inhibition The use intensities of the agents were 9.22 and 8.13, respectively. The strengths of levofloxacin, moxifloxacin and cefminox were all ranked in the top 3, and the intensities of levofloxacin, moxifloxacin and cefmenox were ranked at 5. 29, 4. 56, 4. 74 and 2012, respectively, 5.10,3.85. Conclusion The overall management of antimicrobial drugs in hospitals has achieved certain results, but specific measures need to be taken on the use of antimicrobial drugs to strengthen management control.