吸烟进入体内的化学物质具有多种生理活性,能影响和干扰正常的生理生化过程,从而影响一些药物存体内的吸收、分布、代谢和排泄。研究这些过程的规律,了解吸烟同药物的相互作用,为吸烟患者制订合理的用药方案。对药物代谢动学的影响 Katake等给健康成年吸烟和不吸烟受试者口服1、3、7位甲基标记的13C—或14C—咖 Smoking into the body of chemicals has a variety of physiological activity, can affect and interfere with normal physiological and biochemical processes, thus affecting the absorption, distribution, metabolism and excretion of some drug deposits. To study the laws of these processes, to understand the interaction between smoking and drugs, and to formulate reasonable medication regimens for smokers. Effects on Pharmacokinetics Katake et al. Administered orally 1,3,7-methyl-labeled 13C- or 14C-coffee to healthy adult smokers and non-smokers