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二、链霉素:(一)过敏反应:可以有多种多样,以皮疹最多见,过敏性休克最危险。1.临床类型:(1)皮疹:约占过敏反应的50%。(2)过敏性休克:链霉素引起的过敏性休克,过去尚未引起足够注意。据国外报告,由于抗菌素引起过敏性休克的809例中有9例是由链霉素所引起,国内中华儿科杂志发表由链霉素引起的过敏性休克前后已有15例。最近我们调查了国内四个地区在五年中共发生63例,死亡14例,病死率22.2%。其发病率与青霉素过敏性休克之比为1:3.5,而病死率比青霉素高一倍多。临床表现与青霉素过敏性休克大致相同,少数可合并全身麻木、呕吐、大小便失禁、阴道流血等。
Second, streptomycin: (A) allergic reactions: There can be a wide range of the most common rash, the most dangerous anaphylactic shock. 1. Clinical types: (1) rash: about 50% of allergic reactions. (2) anaphylactic shock: streptomycin-induced anaphylactic shock, the past has not attracted enough attention. According to foreign reports, 9 of 809 cases of anaphylactic shock caused by antibiotics are caused by streptomycin. There are 15 cases before and after the release of streptomycin-induced anaphylactic shock in the Chinese Journal of Pediatrics. Recently, we investigated 63 cases of deaths and 14 cases of deaths in 22 districts in the four regions of China. The incidence of penicillin anaphylactic shock ratio of 1: 3.5, while the mortality rate more than double the penicillin. Clinical manifestations and penicillin almost the same as anaphylactic shock, a few may be combined with general numbness, vomiting, incontinence, vaginal bleeding.