论文部分内容阅读
减毒的沙门氏菌是一种非病原性细菌,能靶向肿瘤并产生局部抗肿瘤的效应。减毒的沙门氏菌能选择性地在肿瘤组织中复制,表达编码治疗性蛋白的效应基因是肿瘤基因治疗有应用前景的一种途径,这种方式也将成为目前实体瘤放疗、化疗的一种辅助的治疗方法。
Attenuated Salmonella is a non-pathogenic bacterium that targets tumors and produces a local anti-tumor effect. Attenuated Salmonella can selectively replicate in tumor tissues and express the gene encoding the therapeutic protein as a promising pathway for gene therapy of cancer, which will also become an aid to radiotherapy and chemotherapy of solid tumors at present The treatment.