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我们构造了一个代表由心肌纤维中5个心肌细胞组成的具有不同水平的细胞-细胞耦联的细胞串的等效电路,并对其进行了阻抗分析。我们在10～106Hz的频率范围内测量了跨过整个网络的阻抗。波特图对于1、10和100个通道几乎是可重叠的。对于10~3、10~4和10~5个通道来说,Z的绝对值在10Hz时较低:例如在1个通道时为9.82MΩ,10~5个通道时为6.64MΩ。ΔZ_(1/2)的值在中等水平的耦联情况下向左漂移:如,对一个通道,f_(1/2)是37.8KHz,而对于10~5个通道。f_(1/2)是1.2KHz。对于高水平的耦联来说,波特图由于终膜的原因而含有双重成分。当R_0增加到8倍时,Z增加到7.47
We constructed an equivalent circuit representing a cell string with different levels of cell-cell coupling consisting of 5 cardiomyocytes in myofibers and analyzed the impedance. We measured the impedance across the entire network in the frequency range of 10 ~ 106Hz. The Bode plot is almost overlapped for 1, 10, and 100 channels. For 10 ~ 3, 10 ~ 4 and 10 ~ 5 channels, the absolute value of Z is lower at 10Hz: for example, 9.82MΩ for 1 channel and 6.64MΩ for 10 ~ 5 channels. The value of ΔZ_ (1/2) drifts to the left with a moderate level of coupling: for example, f_ (1/2) is 37.8 KHz for one channel and 10 to 5 channels for one channel. f_ (1/2) is 1.2 KHz. For a high level of coupling, the Bode plot contains dual components due to the terminal membrane. When R_0 increases to 8 times, Z increases to 7.47