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目的 探讨放射治疗后不同时间的X线影像变化在食管癌术前加速放射治疗中的临床意义。方法 118例直接手术困难的晚期食管癌接受术前加速放射治疗及手术。将放射治疗后的X线分级及变化 ,结合临床治疗情况进行综合分析。结果 加速术前放射治疗结束后第 2d的食管钡餐造影与第 14d的比较 ,后者的X线分级有明显的升级现象 ;其中由Ⅲ、Ⅳ级上升为Ⅱ、Ⅲ级者最多 ,但无越级上升或降级者。放射治疗后第 14d的X线分级与手术切除率、术后病理反应分级、长期生存率均呈正相关 ,即X线分级越好 ,临床疗效越好。结论 食管癌术前加速放射治疗后的X线影像变化 ,对食管癌的治疗方法选择、预后判断具有重要意义
Objective To investigate the clinical significance of X-ray image changes at different times after radiotherapy in accelerated radiotherapy of esophageal cancer preoperatively. Methods A total of 118 patients with advanced esophageal carcinoma who underwent immediate surgery underwent accelerated preoperative radiotherapy and surgery. Radiotherapy after the X-ray grading and changes, combined with clinical treatment of a comprehensive analysis. Results The preoperative radiotherapy at the end of 2d after esophageal barium meal compared with the 14d, X-ray grading of the latter has a significant upgrade phenomenon; which from Ⅲ, Ⅳ grade to Ⅱ, Ⅲ grade up, but no leapfrog Up or downgrade those. X-ray classification 14 days after radiotherapy and surgical resection rate, postoperative pathological response classification, long-term survival rates were positively correlated, that is, the better the X-ray classification, the better clinical efficacy. Conclusion X-ray image changes of esophageal cancer after accelerated radiation therapy are of great significance for the selection of treatment options and prognosis of esophageal cancer