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目的 探讨炎性乳腺癌的临床特点 ,治疗及预后因素。方法 对 48例炎性乳腺癌的临床资料进行回顾性分析 ,按TNM分期 ,Ⅲb期 38例 ,Ⅳ期 10例 ;无特定的组织学类型 ;48例患者均接受综合治疗。结果 全组病例平均生存期为 32个月 ,3年生存率为 45 .8% ,5年生存率为 33 .3 % ;Ⅲb期生存 5年者有 16例 ,Ⅲb期 1年内死亡者有 5例 ,Ⅳ期 10例中有 6例在 1年内死亡。结论 炎性乳腺癌的治疗主要为诱导化疗、手术、局部放疗及辅助化疗的综合治疗。其预后与乳房皮肤红斑范围、术前对化疗药物的敏感性、腋窝淋巴结转移、局部血管受累、临床分期等有关。
Objective To investigate the clinical features, treatment and prognostic factors of inflammatory breast cancer. Methods The clinical data of 48 cases of inflammatory breast cancer were analyzed retrospectively. According to TNM staging, 38 cases were in stage IIIb, 10 cases were in stage IV; there was no specific histological type; 48 cases were treated with comprehensive therapy. Results The average survival time of the whole group was 32 months, the 3-year survival rate was 45.8%, the 5-year survival rate was 33.3%; in the IIIb stage, there were 16 cases in 5 years; in the IIIb stage, there were 5 deaths within 1 year. For example, 6 out of 10 patients in stage IV died within 1 year. Conclusion The treatment of inflammatory breast cancer is mainly induction chemotherapy, surgery, local radiotherapy and adjuvant chemotherapy. Its prognosis is related to the range of breast skin erythema, preoperative sensitivity to chemotherapy drugs, axillary lymph node metastasis, local vascular involvement, and clinical stage.