汇总分析2326对反复流产夫妇的染色体变化,发现207例异常,占受检人数的4.44％;平衡易位159例,占3.43％。并报告一例世界首报核型。本文结果表明:流产次数与具平衡易位携带者的可能性之间存有平行关系;同源罗伯逊易位携带者妊娠的结局表现流产;染色体不平衡程度大,流产次数多。 A total of 2326 pairs of recurrent miscarriage couples chromosomal changes found 207 anomalies, accounting for 4.44% of the number of subjects; balanced translocation in 159 cases, accounting for 3.43%. And report a case of the world’s first karyotype. The results of this paper show that there is a parallel relationship between the number of abortions and the possibility of having a balanced translocation carrier; the outcome of pregnancy with homologous Robertsonian translocations shows abortion; the degree of chromosome imbalance is large and the number of abortions is frequent.