家族性腺瘤性息肉病一家族3代9人20年治疗观察报告如下(图1)。图1　家族性腺瘤性息肉病一家系图谱Ⅰ代祖父。1979年59岁时出现黏液血便,排便频数、排便不畅伴消瘦乏力,经肠镜检查及病理诊断为结肠息肉病恶变,但拒绝手术。1980年10月60岁死于结肠癌肝转移。祖母健在。Ⅱ代兄妹4 Familial adenomatous polyposis A family of three generations of nine 20-year treatment report is as follows (Figure 1). Figure 1 familial adenomatous polyposis a pedigree generation on behalf of my grandfather. In 1979 59 years old when there was mucus bloody stools, defecation frequency, bowel dysfunction with weight loss, colonoscopy and pathological diagnosis of polyposis coli malignant transformation, but refused to surgery. October 1980 60-year-old died of colon cancer liver metastases. My grandmother is alive. Ⅱ brother and sister on behalf of 4