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目的 :了解新生儿缺氧缺血性脑病 (HIE)急性期转归 ,对患儿远期身心健康的影响及各期脑电图的变化。方法 :统计 88例HIE患儿急性期结果、长期随访 75例HIE患儿及EEG检查。结果 :急性期 3例死亡 (3/ 88) ,神经系统后遗症 2 2例 (2 2 / 88) ,少儿时期心理障碍 11例 (11/ 75 ) ,儿童多动症 18例 (18/ 75 ) ,精神发育迟缓者 7例 (7/ 75 )。EEG异常检出率为 33%～ 6 7% ,相关程度P =0 .2 312。结论 :围产期胎儿窘迫及新生儿窒息是造成HIE的重要因素 ,严重脑损伤将影响患儿日后的生长发育。EEG监测有助于早期诊断早期治疗。
Objective: To understand the outcome of the acute phase of neonatal hypoxic-ischemic encephalopathy (HIE) and its effect on the long-term physical and mental health of the infants and the changes of EEG in different stages. Methods: A total of 88 children with HIE were enrolled in the study. The long-term follow-up of 75 children with HIE and EEG was performed. Results: There were 3 deaths (3/88) in the acute phase, 22 (22/88) in the neurological sequelae, 11 (11/75) in the childhood, 18 (18/75) in the children with ADHD, mental development 7 cases of slow (7/75). EEG anomaly detection rate was 33% ~ 67%, the relevance of P = 0.2212. CONCLUSION: Fetal distress and neonatal asphyxia during perinatal period are important factors contributing to HIE. Severe brain injury will affect the future growth and development of children. EEG monitoring can help early diagnosis of early treatment.