吲哚美辛(indomethacin)又名消炎痛,是常用的解热镇痛药,其不良反应常有食欲减退、恶心、皮疹等.我院在临床应用吲哚美辛的过程中,发生一起病人因po吲哚美辛肠溶片致低血容量性休克.患者张×,男,41a,因高热住院待查.测T39.0℃,心率90beats/min,BP18.0/11.3kPa(135/85 mmHg).病人自诉已高热8d,曾自服APC片无效.鉴于病人高热情况严重,对症嘱患者口服吲哚美辛肠溶片25mg(江苏金坛市制药厂,批号:9504201),服药后40min,病人出现罕见的大汗淋漓,随即出现脸色苍白、四肢湿冷、肢端青紫等症,并诉心悸、胸闷、头晕.测心率120beats/min,BP6.7/5.3kPa(50/40mmHg).此时患者神志尚清,诊断为因大量出汗后所致低血容量性休克.立即快速iv gtt复方氯化钠溶 Indomethacin (indomethacin), also known as indomethacin, is commonly used antipyretic analgesics, and its adverse reactions are often loss of appetite, nausea, rash, etc. In our hospital in the clinical application of indometacin, a patient Due to po indometacin enteric-coated tablets caused hypovolemic shock in patients with Zhang ×, male, 41a, hospitalized for fever due to high fever measured T39.0 ℃, heart rate 90beats / min, BP18.0 / 11.3kPa (135 / 85 mmHg) .Since the patient’s private prosecution has been hot 8d, has self-serving APC tablets invalid .In view of the patient’s high fever, symptomatic Zhu Hospice patients oral indomethacin enteric-coated tablets 25mg (Jiangsu Jintan Pharmaceutical Factory, batch number: 9504201) 40min, the patient appeared rare sweating, then pale, limbs cold and bruising, extremities cyanosis embolism, and complained of palpitations, chest tightness, dizziness .Measure heart rate 120beats / min, BP6.7 / 5.3kPa (50 / 40mmHg). At this point the patient is still clear, diagnosed as hypovolemic shock due to a large number of sweating immediately rapid iv gtt compound sodium chloride solution