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实验动物口服骨痹通天丸5.58g/kg.2.79g/kg,观察本品对炎症反应,局部疼痛和免疫功能的影响。结果表明,骨痹通天丸的两个剂量组对大鼠蛋清性关节肿具有不同程度的抑制作用(P<0.01或0.05);对二甲苯性耳廓肿仅大剂量组具有明显抑制作用(P<0.01);对小鼠热刺激所致的疼痛反应具有不同程度的抑制作用(P<0.01或0.05);对化学刺性疼痛两个剂量组均有明显抑制作用(P<0.01);并可抑制小鼠重要免疫器官的增长和巨噬细胞的吞噬功能(P<0.05),对血清溶血素未显示其效应。
Animals were treated with Oral Tongtian Tongtian 5.58g/kg. 2.79g/kg, observe the effect of this product on inflammation, local pain and immune function. The results showed that the two dose groups of Gufu Tongtian Pill had different degrees of inhibition on rat egg white joint swelling (P<0.01 or 0.05); only the large dose group of p-xylene ear swelling had obvious effect Inhibitory effect (P<0.01); The degree of inhibition of pain response induced by mouse thermal stimulation (P<0.01 or 0.05); Both dose groups of chemically stimulating pain were obvious Inhibitory effect (P<0.01); can inhibit the growth of important immune organs and phagocytic function of macrophages in mice (P<0.05). No effect was shown on serum hemolysin.