论文部分内容阅读
目的分析我院瘫痪患者医院感染的现状及抗生素耐药情况,为临床治疗及抗生素的合理应用提供科学依据。方法选取2010年1月～2011年6月间我院收治的瘫痪患者医院感染病例,对其感染部位细菌学和耐药情况进行综合分析。结果瘫痪患者的医院感染发病率较高,感染部位以呼吸道、泌尿道为主。致病菌以铜绿假单胞菌、肺炎克雷白杆菌、大肠埃希菌等革兰阴性菌感染为主,致病菌有较强的耐药性,并呈高度交叉耐药的特点。结论做好细菌耐药性监测,根据细菌耐药试验及PK/PD(药动学/药效学)理论优化抗菌药物治疗方案对于临床治疗有重要意义。
Objective To analyze the status of nosocomial infections and antibiotic resistance in paralyzed patients in our hospital and provide scientific basis for clinical treatment and rational application of antibiotics. Methods From January 2010 to June 2011 in our hospital admitted paralyzed patients with nosocomial infections, the infection site of bacteriological and drug resistance were analyzed. Results The paralyzed patients had a higher incidence of nosocomial infections, and the infection sites were mainly respiratory and urinary tract. Pathogenic bacteria to Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and other Gram-negative bacteria-based, pathogenic bacteria have strong resistance, and was highly cross-resistant characteristics. Conclusion It is important to monitor the drug resistance of bacteria and to optimize the antibacterial therapy regimen according to the bacterial resistance test and PK / PD (pharmacokinetic / pharmacodynamic) theory.