目的了解锦州地区住院患者梅毒感染状况,预防梅毒医源性感染。方法采用梅毒血清凝集试验和甲苯胺红试验方法,对辽宁医学院附属第三医院2008-2012年期间住院患者送检标本进行检测。对32 717名年龄14~94岁的住院患者进行梅毒抗体联合检测。结果从32 717例住院患者中,检出梅毒螺旋体确证试验阳性429例,阳性率1.31%;检出血清凝集试验阳性148例,阳性率0.45%。2008-2012年各年度确证阳性率依次为0.67%、1.01%、1.33%、1.38%、1.79%。结论该地区住院患者中感染梅毒螺旋体感染率较高,且逐年呈上升趋势,应对住院患者加强筛查,采取预防措施。 Objective To understand the syphilis infection in inpatients in Jinzhou and prevent the infection of syphilis. Methods The syphilis serum agglutination test and toluidine red test method were used to test the specimens of inpatients in the Third Affiliated Hospital of Liaoning Medical College from 2008 to 2012. A total of 32 717 hospitalized patients aged 14 to 94 years were tested for syphilis antibody. Results Among 32 717 hospitalized patients, 429 positive cases of syphilis were identified, the positive rate was 1.31%. The positive rate of serum agglutination test was 148 cases, the positive rate was 0.45%. The positive rates in each year from 2008 to 2012 were 0.67%, 1.01%, 1.33%, 1.38% and 1.79%, respectively. Conclusion The prevalence of infection with Treponema pallidum in hospitalized patients in this area is high, and it is increasing year by year. Patients in hospital should be screened intensively and preventive measures should be taken.