Na~+、K~+-ATP酶广泛存在于多种细胞的细胞膜上。现已证明,纯化的Na~+、K~+-ATP酶,如果重组入含有磷脂的脂质体,有催化ATP水解和运输Na~+、K~+的能力。这些重组实验,为Na~+、K~+-ATP酶就是Na~+泵提供了直接的证据。Na~+、K~+-ATP酶催化ATP水解的同时,能对抗细胞膜两侧的电化学梯 Na ~ +, K ~ + -ATPase is widely found in the cell membrane of many kinds of cells. It has been demonstrated that the purified Na ~ +, K ~ + -ATPase, if recombined into liposomes containing phospholipids, has the ability to catalyze ATP hydrolysis and transport Na ~ +, K ~ +. These recombination experiments provide direct evidence that Na ~ + and K ~ + -ATPase are Na ~ + pumps. Na ~ +, K ~ + -ATPase catalyzed ATP hydrolysis at the same time, against the cell membrane on both sides of the electrochemical ladder