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目的对冰片及其复方的实验研究进行文献再评价,以期为冰片的实验研究提供参考。方法查阅、归纳、整理1999年以来公开发表的有关冰片实验研究的文献,根据实验研究的文献数量、内容等方面,分析冰片研究的现状和趋势。结果冰片的实验研究主要集中于药理学方面,表现为促进血脑屏障开放、抗脑缺血和促吸收作用。生药学、药剂学及其冰片的其它功效、适应症研究较少。结论冰片的开窍醒神功效、佐使理论得到较好阐释,为进一步研究冰片及其复方深层次作用机制提供基础,冰片的生药学、药剂学及其冰片的其它功效、适应症是下一步研究趋势。
OBJECTIVE To re-evaluate the experimental study of borneol and its compound in order to provide a reference for the experimental study of borneol. Methods The literature about the experimental study of borneol, which has been published since 1999, is reviewed, summarized and sorted out. The status and trend of research on borneol are analyzed according to the quantity and content of the experimental studies. Results The experimental study of borneol mainly focused on pharmacology, which showed that the opening of blood-brain barrier, anti-cerebral ischemia and absorption were promoted. Pharmacology, pharmacy and other effects of borneol, less indications. CONCLUSIONS: The theory of borneol is better than that of borneol, so that the theory can be well explained. It provides a basis for further research on the mechanism of action of borneol and its compound. The pharmacokinetics and pharmacology of borneol and other effects of borneol are further indications trend.