通常尿毒症肾功能衰竭和透析治疗肾衰患者常有长年脂代谢异常,肾移植后可发生严重动脉粥样硬化,促使血管病变的发生。移植后约有60％患者高甘油三脂血症很少有改变,而高胆固醇血症相应增高。肾移植后第一年血中甘油三脂水平很快下降,但仍有20％以上患者血中甘油三脂增加。血清中总胆固醇和甘油三脂浓度持续增加,均为动脉硬化的危险因素。约有40％肾移植后患者常死于心血管疾病和闭塞性血管癌病。肾移植后几个月中患者血脂水平仍可作为免疫抑制剂治疗和肾功能稳定的指标,但肾功能稳定并非一定要血脂正常。Kasiske氏等复习201例肾移植高脂血症患者,于术后1～2年内,有27％患者 Often uremia renal failure and dialysis treatment of renal failure often long-term lipid metabolism abnormalities, renal transplantation can occur after severe atherosclerosis, prompting the occurrence of vascular lesions. About 60% of transplant patients with hypertriglyceridemia rarely change, while the corresponding increase in hypercholesterolemia. In the first year after renal transplantation, blood triglyceride levels dropped rapidly, but there was still an increase in blood triglyceride levels in more than 20% of patients. Serum total cholesterol and triglyceride concentrations continued to increase, are atherosclerosis risk factors. About 40% of patients after renal transplantation often die of cardiovascular disease and occlusive vascular cancer. In the first few months after renal transplantation, the level of serum lipids can still be used as an immunosuppressive therapy and indicators of stable renal function, but stable renal function is not necessary to normal blood lipids. Kasiske and other 201 cases of patients with hyperlipemia renal transplantation, within 1 to 2 years after surgery, 27% of patients