目的分析内蒙古自治区2008-2015年手足口病的流行特征和主要致病病原,为手足口病防控提供基础依据。方法应用描述性流行病学方法,对内蒙古自治区2008-2015年手足口病流行进行三间分布和主要病原的统计分析。结果内蒙古自治区2008-2015年累计报告手足口病144 915例,死亡32例,发病高峰主要集中在6~7月份;发病人群主要集中在1~5岁,占总发病数的85.80%;男性发病率高于女性,性别比为1.45∶1;2009年和2011年发病率较高,分别为133.62/10万和94.04/10万,2015年发病率为48.77/10万,为2008年之后发病率最低年份;各盟市中,乌海市发病率最高,达184.83/10万,乌兰察布市最低,为26.35/10万。实验室检测和监测结果提示8年平均病原构成以EV-A71为优势病原(占33.15%),CV-A16次之(占22.42%),其他肠道病毒所占比例接近一半(占44.43%)。结论内蒙古自治区手足口病具有明显的时间、地域、人群流行特征,2015年发病率为2008年之后历年新低,提示未来几年可能出现手足口病发病率升高趋势,甚至可能出现暴发疫情,应通过加强预警监测,做好应急处置准备,加大宣传教育力度等措施来预防手足口病大规模暴发疫情的出现。 Objective To analyze epidemiological characteristics and major pathogenic pathogens of HFMD in Inner Mongolia Autonomous Region from 2008 to 2015 and provide the basis for prevention and control of HFMD. Methods Descriptive epidemiological methods were used to analyze the distribution and major pathogens of HFMD in Inner Mongolia Autonomous Region from 2008 to 2015. Results A total of 144 915 hand-foot-mouth disease cases were reported in Inner Mongolia Autonomous Region from 2008 to 2015, with 32 deaths. The peak incidence mainly concentrated in June to July. The incidence of the disease was mainly in the range of 1 to 5 years old, accounting for 85.80% of the total. The prevalence was higher than that of females, with a sex ratio of 1.45: 1. The incidence rates in 2009 and 2011 were higher at 133.62 / lakh and 94.04 / lakh respectively, with an incidence rate of 48.77 / lakh in 2015, the incidence rate after 2008 The lowest in all the cities; Wuhai City had the highest incidence of 184.83 / 100,000 and the lowest in Wulanchabu was 26.35 / 100,000. Laboratory tests and monitoring results suggested that the average pathogenic burden of EV-A71 was 33.15%, followed by CV-A 16 (22.42%), and other enteroviruses was nearly half (44.43%) in 8-year pathogenicity. . Conclusion HFMD in Inner Mongolia Autonomous Region has obvious characteristics of time, region and population. The incidence of HFMD in 2015 is the lowest in recent years after 2008, suggesting that the incidence of HFMD may increase in the next few years and may even cause outbreaks. Measures such as strengthening early warning and monitoring, preparing for emergency response and intensifying propaganda and education were taken to prevent the outbreak of large-scale outbreak of hand-foot-mouth disease.