多年来,已经发现了CMC患者的多种免疫学缺陷,例如,用念球菌刺激时淋巴细胞的增殖和释放淋巴因子的反应降低;念珠菌或其他抗原诱导的皮肤迟发型超敏反应降低或消失;单核细胞和粒细胞的趋化性反应不良;器官特异性自身抗体的发生率增加;血清补体活性低;血清和唾液IgA缺乏;以及 Over the years, a number of immunological deficits have been found in patients with CMC, for example, decreased lymphocyte proliferation and lymphokine release when stimulated with Alcaligenes; reduced or absent or delayed skin delayed hypersensitivity induced by Candida or other antigens ; Poor chemotactic response of monocytes and granulocytes; increased incidence of organ-specific autoantibodies; low serum complement activity; lack of serum and salivary IgA; and