固体上栽培蘑菇菌子实体在各国都已有多年的历史(裘维蕃,1952;Stoller,1954;Robinson和Davidson,1959),而蘑菇菌的深层培养却还是近十多年来的研究。较早的是Humfeld在1948年报导了洋蘑菇(Agaricus campestris)菌丝的深层培养,并指出实际应用的可能性。随后Humfeld和Sugihara(1949,1952,1954)研究深层培养下洋蘑菇 Solid fruiting bodies of mushrooms have been cultivated in many countries for many years (Chow, 1952; Stoller, 1954; Robinson and Davidson, 1959). However, the deep culture of mushrooms is still a research for more than a decade. Earlier, Humfeld reported in 1948 the in-depth culture of Agaricus campestris mycelium and pointed out the possibility of its practical application. Subsequent Humfeld and Sugihara (1949, 1952, 1954) study of deep-sea mushroom cultivation