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为了解前列腺癌临床流行病学情况,对上海市市区前列腺癌新发病例进行全人群对照研究。238例前列腺癌年龄构成为:50岁~11例(4.6%),60岁~64例(26.9%),70岁~115例(48.3%),80岁~45例(18.9%),90~93岁3例(1.3%)。肛指检查阳性率65.5%,合并良性前列腺增生症占56.3%。临床分期T112例(5.4%),T288例(39.8%),T384例(38.0%),T437例(16.8%)。90例(37.8%)确定有远处转移。220例(92.4%)细胞类型为腺癌。184例患者病理分级1级23例(12.5%),2级73例(39.7%),3级88例(47.8%)。临床分期与肿瘤远处转移率有关(P<0.001)。平均血清PSA为87.3μg/L,与人群对照组及BPH对照组有显著性差异(P<0.001)。对血清PSA的价值,前列腺癌的治疗方法进行了初步探讨。
To understand the clinical epidemiology of prostate cancer, a population-based comparative study of newly diagnosed prostate cancer patients in Shanghai was conducted. The age of 238 cases of prostate cancer consisted of 50 to 11 cases (4.6%), 60 to 64 cases (26.9%), 70 to 115 cases (48.3%) and 80 to 45 cases 18.9%), 3 cases (1.3%) 90-93 years old. Anal check positive rate of 65.5%, combined benign prostatic hyperplasia accounted for 56.3%. The clinical stage of T112 cases (5.4%), T288 cases (39.8%), T384 cases (38.0%), T437 cases (16.8%). 90 cases (37.8%) identified distant metastasis. 220 cases (92.4%) of the cell types of adenocarcinoma. The pathological grade of the 184 patients was 23 (12.5%) of grade 1, 73 of grade 2 (39.7%) and 88 of grade 3 (47.8%). The clinical stage was related to distant metastasis of tumor (P <0.001). The mean serum PSA was 87.3 μg / L, which was significantly different from the control group and BPH control group (P <0.001). The value of serum PSA, prostate cancer treatment methods were initially explored.