地中海贫血(地贫)是一组遗传性溶血性贫血,定期输血,慢性溶血以及铁的生物利用度减少,最终导致铁的大量沉积,引起机体各系统脏器功能损害,尤其是内分泌功能损害。随着对地贫患者铁负荷及其内分泌功能研究的不断深入,对临床指导铁超负荷的地贫患儿除铁治疗有很大的理论和实践指 Thalassemia (thalassemia) is a group of hereditary hemolytic anemia, regular blood transfusion, chronic hemolysis and reduced bioavailability of iron, eventually leading to a large number of deposition of iron, causing organ dysfunction in various systems of the body, especially endocrine dysfunction. With the deepening of studies on the iron overload and its endocrine function in thalassemia patients, there is a great deal of theory and practice in the clinical management of iron-depleted thalassemia patients